Open AccessBilirubin and Stroke Risk Using a Mendelian Randomization Design
Author(s) -
Sun Ju Lee,
Yon Ho Jee,
Keum Ji Jung,
Seri Hong,
EunSoon Shin,
Sun Ha Jee
Publication year - 2017
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.015083
Subject(s) - mendelian randomization , medicine , bilirubin , single nucleotide polymorphism , stroke (engine) , genetics , gene , genotype , genetic variants , biology , mechanical engineering , engineering
Circulating bilirubin, a natural antioxidant, is associated with decreased risk of stroke. However, the nature of the relationship between the two remains unknown. We used a Mendelian randomization analysis to assess the causal effect of serum bilirubin on stroke risk in Koreans.
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