Cystatin C Is a Crucial Endogenous Protective Determinant Against Stroke | Zendy

Zongping Fang | Zendy; Jiao Deng | Zendy; Zhixin Wu | Zendy; Beibei Dong | Zendy; Shiquan Wang | Zendy; Xiaodan Chen | Zendy; Huang Nie | Zendy; Hailong Dong | Zendy; Lize Xiong | Zendy

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Cystatin C Is a Crucial Endogenous Protective Determinant Against Stroke

Author(s) -

Zongping Fang,

Jiao Deng,

Zhixin Wu,

Beibei Dong,

Shiquan Wang,

Xiaodan Chen,

Huang Nie,

Hailong Dong,

Lize Xiong

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014975

Subject(s) - neuroprotection , endogeny , medicine , pharmacology , ischemia , ischemic preconditioning , western blot , stroke (engine) , gene knockdown , cystatin c , knockout mouse , apoptosis , biochemistry , biology , receptor , gene , mechanical engineering , engineering , renal function

Endogenous neuroprotection can be induced by ischemic and nonischemic preconditioning. However, not all subjects that undergo preconditioning exhibit similar favorable outcome. This study is to explore the molecules responsible for this phenomenon and find new therapeutic targets for stroke.

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