Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model | Zendy

Hiroki Uchida | Zendy; Kuniyasu Niizuma | Zendy; Yoshihiro Kushida | Zendy; Shohei Wakao | Zendy; Teiji Tominaga | Zendy; Cesar V. Borlongan | Zendy; Mari Dezawa | Zendy

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Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model

Author(s) -

Hiroki Uchida,

Kuniyasu Niizuma,

Yoshihiro Kushida,

Shohei Wakao,

Teiji Tominaga,

Cesar V. Borlongan,

Mari Dezawa

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014950

Subject(s) - medicine , transplantation , neun , pathology , mesenchymal stem cell , induced pluripotent stem cell , stem cell , neural stem cell , bone marrow , corticospinal tract , anatomy , microbiology and biotechnology , biology , surgery , embryonic stem cell , magnetic resonance imaging , biochemistry , immunohistochemistry , radiology , diffusion mri , gene

Multilineage-differentiating stress-enduring (muse) cells are endogenous nontumorigenic stem cells with pluripotency harvestable as pluripotent marker SSEA-3 + cells from the bone marrow from cultured bone marrow-mesenchymal stem cells. After transplantation into neurological disease models, muse cells exert repair effects, but the exact mechanism remains inconclusive.

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