Impaired Collateral Flow Compensation During Chronic Cerebral Hypoperfusion in the Type 2 Diabetic Mice | Zendy

Yasuo Nishijima | Zendy; Yosuke Akamatsu | Zendy; Shih Yen Yang | Zendy; Chih Cheng Lee | Zendy; Utku Baran | Zendy; Shaozhen Song | Zendy; Ruikang K. Wang | Zendy; Teiji Tominaga | Zendy; Jialing Liu | Zendy

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Impaired Collateral Flow Compensation During Chronic Cerebral Hypoperfusion in the Type 2 Diabetic Mice

Author(s) -

Yasuo Nishijima,

Yosuke Akamatsu,

Shih Yen Yang,

Chih Cheng Lee,

Utku Baran,

Shaozhen Song,

Ruikang K. Wang,

Teiji Tominaga,

Jialing Liu

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014882

Subject(s) - circle of willis , medicine , anterior cerebral artery , cerebral arteries , middle cerebral artery , cardiology , anterior communicating artery , perfusion , collateral circulation , cerebral blood flow , diabetes mellitus , common carotid artery , internal carotid artery , occlusion , artery , perforating arteries , ischemia , carotid arteries , endocrinology , subarachnoid hemorrhage

The presence of collaterals is associated with a reduced risk of stroke and transient ischemic attack in patients with steno-occlusive carotid artery disease. Although metabolic syndrome negatively impacts collateral status, it is unclear whether and to what extent type 2 diabetes mellitus affects cerebral collateral flow regulation during hypoperfusion.

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