Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke | Zendy

Isabel BravoFerrer | Zendy; María Isabel Cuartero | Zendy; Juan G. Zarruk | Zendy; Jesús M. Pradillo | Zendy; Olivia Hurtado | Zendy; Víctor G. Romera | Zendy; Javier Díaz-Alonso | Zendy; Juan M. GarcíaSegura | Zendy; Manuel Guzmán | Zendy; Ignacio Lizasoaín | Zendy; Ismael GalveRoperh | Zendy; Marı́a A. Moro | Zendy

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Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke

Author(s) -

Isabel BravoFerrer,

María Isabel Cuartero,

Juan G. Zarruk,

Jesús M. Pradillo,

Olivia Hurtado,

Víctor G. Romera,

Javier Díaz-Alonso,

Juan M. GarcíaSegura,

Manuel Guzmán,

Ignacio Lizasoaín,

Ismael GalveRoperh,

Marı́a A. Moro

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014793

Subject(s) - neun , neurogenesis , medicine , stroke (engine) , neuroprotection , agonist , cannabinoid , endocrinology , pharmacology , neuroscience , receptor , psychology , mechanical engineering , immunohistochemistry , engineering

Stroke is a leading cause of adult disability characterized by physical, cognitive, and emotional disturbances. Unfortunately, pharmacological options are scarce. The cannabinoid type-2 receptor (CB2R) is neuroprotective in acute experimental stroke by anti-inflammatory mechanisms. However, its role in chronic stroke is still unknown.

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