Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling
Author(s) -
George Harston,
Thomas W. Okell,
Fintan Sheerin,
Ursula G. Schulz,
P Mathieson,
Ian Reckless,
Kunal Shah,
Gary A. Ford,
Michael A. Chappell,
Peter Jezzard,
James Kennedy
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.014707
Subject(s) - medicine , arterial spin labeling , cerebral blood flow , stroke (engine) , acute stroke , cardiology , blood flow , cerebrovascular circulation , anesthesia , mechanical engineering , engineering , tissue plasminogen activator
Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset.
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