Acupuncture Attenuated Vascular Dementia–Induced Hippocampal Long-Term Potentiation Impairments via Activation of D1/D5 Receptors
Author(s) -
Ye Yang,
Hui Li,
JingWen Yang,
Xuerui Wang,
GuangXia Shi,
Chao-Qun Yan,
SiMing Ma,
Wen Zhu,
Qianqian Li,
Tianran Li,
LingYong Xiao,
CunZhi Liu
Publication year - 2017
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.014696
Subject(s) - medicine , morris water navigation task , long term potentiation , hippocampus , neuroscience , vascular dementia , synaptic plasticity , dopamine , acupuncture , dentate gyrus , hippocampal formation , dementia , receptor , psychology , pathology , alternative medicine , disease
Emerging evidence suggests that acupuncture could improve cognitive impairment in vascular dementia by enhancing synaptic plasticity in the hippocampus. The purpose of this study is to investigate whether dopamine, a key mediator of synaptic plasticity, is involved in this cognitive improvement.
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