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Microsurgery for ARUBA Trial (A Randomized Trial of Unruptured Brain Arteriovenous Malformation)–Eligible Unruptured Brain Arteriovenous Malformations
Author(s) -
Johnny Wong,
Alana Slomovic,
George M. Ibrahim,
Ivan Radovanovic,
Michael Tymianski
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.014660
Subject(s) - medicine , modified rankin scale , microsurgery , arteriovenous malformation , randomized controlled trial , surgery , embolization , population , randomization , radiosurgery , ischemic stroke , environmental health , ischemia , radiation therapy
The management of unruptured brain arteriovenous malformations (ubAVMs) remains controversial despite ARUBA trial (A Randomized Trial of Unruptured Brain Arteriovenous Malformation), a controlled trial that suggested superiority of conservative management over intervention. However, microsurgery occurred in only 14.9% of ARUBA intervention cases, raising concerns about the study's generalizability. Our purpose was to evaluate whether, in a larger ARUBA-eligible ubAVM population, microsurgery produces acceptable outcomes.

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