Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults | Zendy

Pauline Schaapsmeerders | Zendy; Anil M. Tuladhar | Zendy; Renate M. Arntz | Zendy; Sieske Franssen | Zendy; Noortje A.M. Maaijwee | Zendy; Loes C.A. RuttenJacobs | Zendy; Hennie C. Schoonderwaldt | Zendy; Lucille D.A. Dorresteijn | Zendy; Ewoud J. van Dijk | Zendy; Roy P. C. Kessels | Zendy; Frank–Erik de Leeuw | Zendy

Open Access

Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults

Author(s) -

Pauline Schaapsmeerders,

Anil M. Tuladhar,

Renate M. Arntz,

Sieske Franssen,

Noortje A.M. Maaijwee,

Loes C.A. RuttenJacobs,

Hennie C. Schoonderwaldt,

Lucille D.A. Dorresteijn,

Ewoud J. van Dijk,

Roy P. C. Kessels,

Frank–Erik de Leeuw

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014356

Subject(s) - medicine , cognitive impairment , white matter , ischemic stroke , stroke (engine) , cognition , cardiology , ischemia , psychiatry , magnetic resonance imaging , radiology , mechanical engineering , engineering

Poststroke cognitive impairment occurs frequently in young patients with ischemic stroke (18 through 50 years of age). Accumulating data suggest that stroke is associated with lower white matter integrity remote from the stroke impact area, which might explain why some patients have good long-term cognitive outcome and others do not. Given the life expectancy of decades in young patients, we therefore investigated remote white matter in relation to long-term cognitive function.

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