Validation of Noninvasive In Vivo Compound Ultrasound Strain Imaging Using Histologic Plaque Vulnerability Features | Zendy

Hendrik H.G. Hansen | Zendy; Gert J. de Borst | Zendy; Michiel L. Bots | Zendy; Frans L. Moll | Zendy; Gerard Pasterkamp | Zendy; Chris L. de Korte | Zendy

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Validation of Noninvasive In Vivo Compound Ultrasound Strain Imaging Using Histologic Plaque Vulnerability Features

Author(s) -

Hendrik H.G. Hansen,

Gert J. de Borst,

Michiel L. Bots,

Frans L. Moll,

Gerard Pasterkamp,

Chris L. de Korte

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.014139

Subject(s) - medicine , fibrous cap , ultrasound , vulnerable plaque , carotid endarterectomy , atheroma , lumen (anatomy) , strain (injury) , stroke (engine) , histology , endarterectomy , radiology , pathology , cardiology , stenosis , mechanical engineering , engineering

Carotid plaque rupture is a major cause of stroke. Key issue for risk stratification is early identification of rupture-prone plaques. A noninvasive technique, compound ultrasound strain imaging, was developed providing high-resolution radial deformation/strain images of atherosclerotic plaques. This study aims at in vivo validation of compound ultrasound strain imaging in patients by relating the measured strains to typical features of vulnerable plaques derived from histology after carotid endarterectomy.

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