Good Intracranial Collaterals Trump Poor ASPECTS (Alberta Stroke Program Early CT Score) for Intravenous Thrombolysis in Anterior Circulation Acute Ischemic Stroke | Zendy

Benjamin YongQiang Tan | Zendy; Wan Yee Kong | Zendy; Prakash Paliwal | Zendy; Anil Gopinathan | Zendy; Mahendran Nadarajah | Zendy; Eric Ting | Zendy; Narayanaswamy Venketasubramanian | Zendy; Raymond C.S. Seet | Zendy; Bernard P.L. Chan | Zendy; Hock Luen Teoh | Zendy; Rahul Rathakrishnan | Zendy; Vijay K. Sharma | Zendy; Leonard L.L. Yeo | Zendy

Open Access

Good Intracranial Collaterals Trump Poor ASPECTS (Alberta Stroke Program Early CT Score) for Intravenous Thrombolysis in Anterior Circulation Acute Ischemic Stroke

Author(s) -

Benjamin YongQiang Tan,

Wan Yee Kong,

Prakash Paliwal,

Anil Gopinathan,

Mahendran Nadarajah,

Eric Ting,

Narayanaswamy Venketasubramanian,

Raymond C.S. Seet,

Bernard P.L. Chan,

Hock Luen Teoh,

Rahul Rathakrishnan,

Vijay K. Sharma,

Leonard L.L. Yeo

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.013879

Subject(s) - medicine , thrombolysis , stroke (engine) , ischemic stroke , acute stroke , collateral circulation , cardiology , circulation (fluid dynamics) , brain ischemia , anesthesia , ischemia , tissue plasminogen activator , myocardial infarction , mechanical engineering , engineering , physics , thermodynamics

In acute ischemic stroke, large early infarct size estimated by the Alberta Stroke Program Early CT Score (ASPECTS) is associated with poorer outcomes and is a relative contraindication for recanalization therapies. The state of the intracranial collateral circulation influences the functional outcome and may be a variable to consider before thrombolysis. We evaluated the prognostic effect of the collateral circulation in patients with thrombolyzed acute ischemic stroke who have large early infarct sizes as indicated by low ASPECTS.

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