Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci
Author(s) -
Cheryl Dykstra-Aiello,
Glen C. Jickling,
Bradley P. Ander,
Natasha Shroff,
Xinhua Zhan,
Dazhi Liu,
Heather Hull,
Miles Orantia,
Boryana Stamova,
Frank R. Sharp
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.013869
Subject(s) - medicine , stroke (engine) , sexual dimorphism , gene expression , confounding , bioinformatics , gene , biology , genetics , engineering , mechanical engineering
Although peripheral blood mRNA and micro-RNA change after ischemic stroke, any role for long noncoding RNA (lncRNA), which comprise most of the genome and have been implicated in various diseases, is unknown. Thus, we hypothesized that lncRNA expression also changes after stroke.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom