Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania
Author(s) -
Quirijn de Mast,
Jessica E. Molhoek,
André van der Ven,
William K. Gray,
Philip G. de Groot,
Ahmed Jusabani,
Ferdinand Mugusi,
Rolf T. Urbanus,
Richard Walker
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.013760
Subject(s) - medicine , odds ratio , lupus anticoagulant , stroke (engine) , confidence interval , immunology , tanzania , population , risk factor , hazard ratio , antibody , environmental health , mechanical engineering , environmental science , environmental planning , engineering
The burden of stroke is high in sub-Saharan Africa, and improved knowledge of risk factors is needed. Antiphospholipid antibodies are a common acquired stroke risk factor in young individuals. Antiphospholipid antibodies may be induced by infectious diseases. Sub-Saharan Africa has a high infectious burden, and we analyzed the contribution of antiphospholipid antibodies to the risk of stroke in an incident population from rural and urban Tanzania.
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