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Letter by Kawada Regarding Article, “Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People”
Author(s) -
Tomoyuki Kawada
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.013170
Subject(s) - arteriolosclerosis , medicine , autopsy , gerontology , epidemiology , pathology , disease
Lim et al1 examined the relationship between sleep fragmentation and the histopathologic measures of cerebrovascular disease using data from 315 autopsied older inhabitants. The authors used actigraphy for the measurement of sleep fragmentation before death and the severity of vascular pathology and the presence/absence of brain infarct after death at autopsy. Ordinal logistic regression models were adopted to analyze the relationships, and they concluded that sleep fragmentation was significantly associated with arteriolosclerosis and the presence of subcortical infarcts. I …

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