Thrombus Histology Suggests Cardioembolic Cause in Cryptogenic Stroke
Author(s) -
Tobias BoeckhBehrens,
Justus F. Kleine,
Claus Zimmer,
Frauke Neff,
Fabian Scheipl,
Jaroslav Pelisek,
Lucas Schirmer,
Kim Phung Nguyen,
Deniz Karataş,
Holger Poppert
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.013105
Subject(s) - medicine , thrombus , stroke (engine) , cardiology , fibrin , platelet , brain ischemia , ischemia , occlusion , pathology , radiology , mechanical engineering , immunology , engineering
Ischemic stroke of undetermined cause is a major health issue because of its high frequency and clinical relevance. Histopathologic analysis of human thrombi, retrieved from stroke patients with large-vessel occlusion during mechanical thrombectomy, may provide information about underlying pathologies. This study examines the relationship between stroke causes and histological clot composition to identify specific patterns that might help to distinguish causes of cryptogenic stroke.
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