Progressive Cortical Neuronal Damage and Chronic Hemodynamic Impairment in Atherosclerotic Major Cerebral Artery Disease | Zendy

Hiroshi Yamauchi | Zendy; Shinya Kagawa | Zendy; Yoshihiko Kishibe | Zendy; Masaaki Takahashi | Zendy; Tatsuya Higashi | Zendy

Open Access

Progressive Cortical Neuronal Damage and Chronic Hemodynamic Impairment in Atherosclerotic Major Cerebral Artery Disease

Author(s) -

Hiroshi Yamauchi,

Shinya Kagawa,

Yoshihiko Kishibe,

Masaaki Takahashi,

Tatsuya Higashi

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.013093

Subject(s) - medicine , hemodynamics , cardiology , middle cerebral artery , internal carotid artery , cerebral blood flow , carotid artery disease , anesthesia , ischemia , carotid arteries , carotid endarterectomy

Cross-sectional studies suggest that chronic hemodynamic impairment may cause selective cortical neuronal damage in patients with atherosclerotic internal carotid artery or middle cerebral artery occlusive disease. The purpose of this longitudinal study was to determine whether the progression of cortical neuronal damage, evaluated as a decrease in central benzodiazepine receptors (BZRs), is associated with hemodynamic impairment at baseline or hemodynamic deterioration during follow-up.

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