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Nonatheroscleotic Isolated Middle Cerebral Artery Disease May Be Early Manifestation of Moyamoya Disease
Author(s) -
YeonJung Kim,
Joo Kyung Lee,
SungHo Ahn,
Bum Joon Kim,
DongWha Kang,
SeonOk Kim,
Sun U. Kwon
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.116.012751
Subject(s) - medicine , moyamoya disease , pathogenesis , stroke (engine) , cardiology , cerebral arteries , vascular disease , magnetic resonance imaging , magnetic resonance angiography , etiology , vasculitis , disease , pathology , radiology , mechanical engineering , engineering
Middle cerebral artery steno-occlusive disease (MCAD) is not an uncommon cause of ischemic stroke in young Asians. Aside from atherosclerosis, the pathogenesis of MCAD include various nonatherosclerotic vasculopathies, most of which are yet to be defined. This study investigated the pathogenesis of symptomatic isolated MCAD in young Asian patients using high-resolution magnetic resonance imaging (HR-MRI) and mutation analysis of RNF213.

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