RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture | Zendy

Rachel Kleinloog | Zendy; Bon H. Verweij | Zendy; Pieter van der Vlies | Zendy; Patrick Deelen | Zendy; Morris A. Swertz | Zendy; Louis De Muynck | Zendy; Philip Van Damme | Zendy; Fabrizio Giuliani | Zendy; Luca Regli | Zendy; Albert van der Zwan | Zendy; Jan Willem Berkelbach van der Sprenkel | Zendy; Kiwan Han | Zendy; Peter H. Gosselaar | Zendy; Peter C. van Rijen | Zendy; Emine Korkmaz | Zendy; Jan A. Post | Zendy; Gabriël J.E. Rinkel | Zendy; Jan H. Veldink | Zendy; Ynte M. Ruigrok | Zendy

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RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture

Author(s) -

Rachel Kleinloog,

Bon H. Verweij,

Pieter van der Vlies,

Patrick Deelen,

Morris A. Swertz,

Louis De Muynck,

Philip Van Damme,

Fabrizio Giuliani,

Luca Regli,

Albert van der Zwan,

Jan Willem Berkelbach van der Sprenkel,

Kiwan Han,

Peter H. Gosselaar,

Peter C. van Rijen,

Emine Korkmaz,

Jan A. Post,

Gabriël J.E. Rinkel,

Jan H. Veldink,

Ynte M. Ruigrok

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.116.012541

Subject(s) - medicine , pathogenesis , aneurysm , gene expression , immune system , gene , extracellular matrix , antibody , pathology , immunology , biology , radiology , microbiology and biotechnology , genetics

Analyzing genes involved in development and rupture of intracranial aneurysms can enhance knowledge about the pathogenesis of aneurysms, and identify new treatment strategies. We compared gene expression between ruptured and unruptured aneurysms and control intracranial arteries.

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