Open AccessSignificance of Cerebral Small-Vessel Disease in Acute Intracerebral Hemorrhage
Author(s) -
Shoichiro Sato,
Candice Delcourt,
Emma Heeley,
Hisatomi Arima,
Shihong Zhang,
Rustam AlShahi Salman,
Christian Stapf,
Daniel Woo,
Matthew L. Flaherty,
Achala Vagal,
Christopher Levi,
Leo Davies,
JiGuang Wang,
Thompson Robinson,
Pablo M. Lavados,
Richard I. Lindley,
John Chalmers,
Craig S. Anderson
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.115.012147
Subject(s) - medicine , intracerebral hemorrhage , atrophy , cerebral atrophy , hyperintensity , cardiology , odds ratio , stroke (engine) , blood pressure , confidence interval , hazard ratio , anesthesia , radiology , magnetic resonance imaging , subarachnoid hemorrhage , mechanical engineering , engineering
The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations of cerebral SVD and outcomes, and in terms of any differential effect of early intensive blood pressure-lowering treatment, in the large-scale Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2).
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