Response to Letter Regarding Article, “Periprocedural Myocardial Infarction After Aarotid Endarterectomy and Stenting: Systematic Review and Meta-Analysis” | Zendy

Marion Boulanger | Zendy; Emmanuel Touzé | Zendy

Open Access

Response to Letter Regarding Article, “Periprocedural Myocardial Infarction After Aarotid Endarterectomy and Stenting: Systematic Review and Meta-Analysis”

Author(s) -

Marion Boulanger,

Emmanuel Touzé

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.115.011675

Subject(s) - medicine , myocardial infarction , carotid endarterectomy , meta analysis , endarterectomy , carotid stenting , cardiology , surgery , general surgery , carotid arteries

We thank Dr Galyfos et al1 for their comments on our article. Unfortunately, the diagnostic criteria for myocardial infarction (MI) was unspecified in most of the included studies, leaving the possibility of misclassification bias. However, it is unlikely that differential misclassification bias based on carotid intervention has occurred and all except one of the studies, which described MI criteria met the latest definition of MI.2 When pooling absolute risks, heterogeneity is common and can result from variation in outcome definition, but most commonly from case mix. Random models are used to take this into account.Despite variations in MI definition by international guidelines and improvement of periprocedural management, no statistically significant variation in absolute risks of MI after carotid endarterectomy (CEA) and carotid angioplasty and stenting (CAS) were …

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