Open AccessSleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People
Author(s) -
Andrew Lim,
Lei Yu,
Julie A. Schneider,
David A. Bennett,
Aron S. Buchman
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.115.011608
Subject(s) - arteriolosclerosis , medicine , odds ratio , cerebral amyloid angiopathy , autopsy , confidence interval , cardiology , pathology , dementia , disease
Although several forms of sleep disruption are associated with stroke, few studies have examined the relationship between sleep and histopathologic measures of cerebrovascular disease. We tested the hypothesis that greater sleep fragmentation is associated with a higher burden of cerebral vessel and infarct pathology at autopsy.
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