Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats | Zendy

Jiang Wu | Zendy; Yang Zhang | Zendy; Peng Yang | Zendy; Budbazar Enkhjargal | Zendy; Anatol Manaenko | Zendy; Jiping Tang | Zendy; William J. Pearce | Zendy; Richard E. Hartman | Zendy; André Obenaus | Zendy; Gang Chen | Zendy; John H. Zhang | Zendy

Open Access

Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats

Author(s) -

Jiang Wu,

Yang Zhang,

Peng Yang,

Budbazar Enkhjargal,

Anatol Manaenko,

Jiping Tang,

William J. Pearce,

Richard E. Hartman,

André Obenaus,

Gang Chen,

John H. Zhang

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.115.011552

Subject(s) - medicine , vascular smooth muscle , small interfering rna , subarachnoid hemorrhage , integrin , fibronectin , pathology , receptor , microbiology and biotechnology , extracellular matrix , biology , cell culture , transfection , smooth muscle , genetics

Recombinant osteopontin (rOPN) has been reported to be neuroprotective in stroke animal models. The purpose of this study is to investigate a potential role and mechanism of nasal administration of rOPN on preserving the vascular smooth muscle phenotype in early brain injury after subarachnoid hemorrhage (SAH).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research