Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis?
Author(s) -
Felix Wei,
K. Diedrich,
Heather J. Fullerton,
Gabrielle deVeber,
Max Wintermark,
Jacquie Hodge,
Adam Kirton,
MM Dowling,
S. RAVAUD BENEDICT,
TJ Bernard,
Christine K. Fox,
Neil Friedman,
WD Lo,
RN Ichord,
MA Tan,
M Mackay,
Marta Hernández,
Peter Humphreys,
LC Jordan,
SM Sultan,
MJ Rivkin,
MF Rafay,
Luigi Titomanlio,
Gordana Kovačević,
JY Yager,
Catherine AmlieLefond,
Nomazulu Dlamini,
John Condie,
E. Ann Yeh,
Rachel Kneen,
Bruce Björnson,
Paola Pergami,
LP Zou,
Jorina Elbers,
Abdalla Abdalla,
Anthony K.C. Chan,
Osman Farooq,
Ming Lim,
J. B. Carpenter,
Steven G. Pavlakis,
Vcn Wong,
Rob Forsyth
Publication year - 2016
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.115.011331
Subject(s) - medicine , tortuosity , arterial dissection , stroke (engine) , cardiology , cerebral arteries , dissection (medical) , pediatric stroke , radiology , anesthesia , ischemia , ischemic stroke , mechanical engineering , geotechnical engineering , porosity , engineering
Arteriopathy is the leading cause of childhood arterial ischemic stroke. Mechanisms are poorly understood but may include inherent abnormalities of arterial structure. Extracranial dissection is associated with connective tissue disorders in adult stroke. Focal cerebral arteriopathy is a common syndrome where pathophysiology is unknown but may include intracranial dissection or transient cerebral arteriopathy. We aimed to quantify cerebral arterial tortuosity in childhood arterial ischemic stroke, hypothesizing increased tortuosity in dissection.
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