Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke | Zendy

Anne Broeg-Morvay | Zendy; Pasquale Mordasini | Zendy; Corrado Bernasconi | Zendy; Monika Bühlmann | Zendy; Frauke Pult | Zendy; Marcel Arnold | Zendy; Gerhard Schroth | Zendy; Simon Jung | Zendy; Heinrich P. Mattle | Zendy; Jan Gralla | Zendy; Urs Fischer | Zendy

Open Access

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke

Author(s) -

Anne Broeg-Morvay,

Pasquale Mordasini,

Corrado Bernasconi,

Monika Bühlmann,

Frauke Pult,

Marcel Arnold,

Gerhard Schroth,

Simon Jung,

Heinrich P. Mattle,

Jan Gralla,

Urs Fischer

Publication year - 2016

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.115.011134

Subject(s) - medicine , thrombolysis , modified rankin scale , intracerebral hemorrhage , stroke (engine) , anterior cerebral artery , propensity score matching , randomized controlled trial , cardiology , surgery , asymptomatic , middle cerebral artery , myocardial infarction , ischemic stroke , subarachnoid hemorrhage , ischemia , mechanical engineering , engineering

Five randomized controlled trials have consistently shown that mechanical thrombectomy (MT) in addition to best medical treatment (±intravenous tissue-type plasminogen activator) improves outcome after acute ischemic stroke in patients with large artery anterior circulation stroke. Whether direct MT is equally effective as combined intravenous thrombolysis with MT (ie, bridging thrombolysis) remains unclear.

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