Glyceryl Trinitrate for Acute Intracerebral Hemorrhage
Author(s) -
Kailash Krishnan,
Polly Scutt,
Lisa J Woodhouse,
Alessandro Adami,
Jennifer Becker,
Eivind Berge,
Lesley Cala,
Ana M. Casado,
Valeria Caso,
Christopher Chen,
Hanne Christensen,
Rónán Collins,
Anna Członkowska,
Robert A. Dineen,
John Gommans,
Panos Koumellis,
Kennedy R. Lees,
George Ntaios,
Şerefnur Öztürk,
Stephen Phillips,
Stuart J. Pocock,
Asita de Silva,
Nikola Sprigg,
Szabolcs Szatmári,
Joanna M. Wardlaw,
Philip M. Bath
Publication year - 2015
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.115.010368
Subject(s) - medicine , modified rankin scale , intracerebral hemorrhage , confidence interval , odds ratio , anesthesia , stroke (engine) , blood pressure , randomized controlled trial , subgroup analysis , subarachnoid hemorrhage , ischemic stroke , mechanical engineering , ischemia , engineering
The Efficacy of Nitric Oxide in Stroke (ENOS) trial found that transdermal glyceryl trinitrate (GTN, a nitric oxide donor) lowered blood pressure but did not improve functional outcome in patients with acute stroke. However, GTN was associated with improved outcome if patients were randomized within 6 hours of stroke onset.
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