Effects of Blood Pressure and Blood Pressure–Lowering Treatment During the First 24 Hours Among Patients in the Third International Stroke Trial of Thrombolytic Treatment for Acute Ischemic Stroke | Zendy

Eivind Berge | Zendy; Geoffrey Cohen | Zendy; Richard I. Lindley | Zendy; Peter Sandercock | Zendy; Joanna M. Wardlaw | Zendy; Else Charlotte Sandset | Zendy; William Whiteley | Zendy

Open Access

Effects of Blood Pressure and Blood Pressure–Lowering Treatment During the First 24 Hours Among Patients in the Third International Stroke Trial of Thrombolytic Treatment for Acute Ischemic Stroke

Author(s) -

Eivind Berge,

Geoffrey Cohen,

Richard I. Lindley,

Peter Sandercock,

Joanna M. Wardlaw,

Else Charlotte Sandset,

William Whiteley

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.115.010319

Subject(s) - medicine , blood pressure , stroke (engine) , cardiology , randomization , randomized controlled trial , adverse effect , anesthesia , mechanical engineering , engineering

In patients with acute ischemic stroke, a high blood pressure or a highly variable blood pressure is a common reason for withholding thrombolytic treatment, but guidelines recommend a conservative approach to active blood pressure lowering in this setting. We have performed exploratory analyses to study the clinical effects of blood pressure and early blood pressure-lowering treatment in patients included in a randomized-controlled trial of thrombolytic treatment for acute ischemic stroke.

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