Human Carotid Plaques With High Levels of Interleukin-16 Are Associated With Reduced Risk for Cardiovascular Events
Author(s) -
Caitríona Grönberg,
Eva Bengtsson,
Gunilla Nordin Fredrikson,
Mihaela Nitulescu,
Giuseppe Asciutto,
Ana Persson,
Linda Andersson,
Jan Nilsson,
Isabel Gonçalves,
Harry Björkbacka
Publication year - 2015
Publication title -
stroke
Language(s) - English
Resource type - Journals
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.115.009910
Subject(s) - medicine , stroke (engine) , cardiology , interleukin , pathology , cytokine , mechanical engineering , engineering
Interleukin-16 (IL-16) functions as a regulator of T-cell growth and acts as an inducer of cell migration. The aim of this study was to determine whether IL-16 measured in human carotid plaques was associated with symptoms (eg, stroke, transient ischemic attack, or amaurosis fugax), markers of plaque stability, and postoperative cardiovascular events.
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