Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke | Zendy

Ken B. Hanscombe | Zendy; Matthew Traylor | Zendy; Pirro G. Hysi | Zendy; Steve Bevan | Zendy; Martin Dichgans | Zendy; Peter M. Rothwell | Zendy; Bradford B. Worrall | Zendy; Sudha Seshadri | Zendy; Cathie Sudlow | Zendy; Frances M. K. Williams | Zendy; Hugh S. Markus | Zendy; Cathryn M. Lewis | Zendy

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Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke

Author(s) -

Ken B. Hanscombe,

Matthew Traylor,

Pirro G. Hysi,

Steve Bevan,

Martin Dichgans,

Peter M. Rothwell,

Bradford B. Worrall,

Sudha Seshadri,

Cathie Sudlow,

Frances M. K. Williams,

Hugh S. Markus,

Cathryn M. Lewis

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.115.009387

Subject(s) - medicine , single nucleotide polymorphism , concordance , stroke (engine) , genome wide association study , coagulation , risk factor , ischemic stroke , genotype , population , genetic association , bioinformatics , genetics , gene , ischemia , biology , mechanical engineering , environmental health , engineering

Abnormal coagulation has been implicated in the pathogenesis of ischemic stroke, but how this association is mediated and whether it differs between ischemic stroke subtypes is unknown. We determined the shared genetic risk between 14 coagulation factors and ischemic stroke and its subtypes.

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