Job Strain and the Risk of Stroke | Zendy

Eleonor I. Fransson | Zendy; Solja T. Nyberg | Zendy; Katriina Heikkilä | Zendy; Lars Alfredsson | Zendy; Jakob Bue Bjørner | Zendy; Marianne Borritz | Zendy; Hermann Burr | Zendy; Nico Dragano | Zendy; G. Geuskens | Zendy; Marcel Goldberg | Zendy; Mark Hamer | Zendy; W. Hooftman | Zendy; I.L.D. Houtman | Zendy; Matti Joensuu | Zendy; Markus Jokela | Zendy; Anders Knutsson | Zendy; Markku Koskenvuo | Zendy; Aki Koskinen | Zendy; Meena Kumari | Zendy; Constanze Leineweber | Zendy; Thorsten Lunau | Zendy; Ida E. H. Madsen | Zendy; Linda L. Magnusson Hanson | Zendy; Martin L. Nielsen | Zendy; Maria Nordin | Zendy; Tuula Oksanen | Zendy; Jaana Pentti | Zendy; Jan Hyld Pejtersen | Zendy; Reiner Rugulies | Zendy; Paula Salo | Zendy; Martin J. Shipley | Zendy; Andrew Steptoe | Zendy; Sakari Suominen | Zendy; Töres Theorell | Zendy; Salla ToppinenTanner | Zendy; Jussi Vahtera | Zendy; Marianna Virtanen | Zendy; Ari Väänänen | Zendy; Peter Westerholm | Zendy; Hugo Westerlund | Zendy; Marie Zins | Zendy; Annie Britton | Zendy; Eric J. Brunner | Zendy; Archana SinghManoux | Zendy; G. David Batty | Zendy; Mika Kivimäki | Zendy

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Job Strain and the Risk of Stroke

Author(s) -

Eleonor I. Fransson,

Solja T. Nyberg,

Katriina Heikkilä,

Lars Alfredsson,

Jakob Bue Bjørner,

Marianne Borritz,

Hermann Burr,

Nico Dragano,

G. Geuskens,

Marcel Goldberg,

Mark Hamer,

W. Hooftman,

I.L.D. Houtman,

Matti Joensuu,

Markus Jokela,

Anders Knutsson,

Markku Koskenvuo,

Aki Koskinen,

Meena Kumari,

Constanze Leineweber,

Thorsten Lunau,

Ida E. H. Madsen,

Linda L. Magnusson Hanson,

Martin L. Nielsen,

Maria Nordin,

Tuula Oksanen,

Jaana Pentti,

Jan Hyld Pejtersen,

Reiner Rugulies,

Paula Salo,

Martin J. Shipley,

Andrew Steptoe,

Sakari Suominen,

Töres Theorell,

Salla ToppinenTanner,

Jussi Vahtera,

Marianna Virtanen,

Ari Väänänen,

Peter Westerholm,

Hugo Westerlund,

Marie Zins,

Annie Britton,

Eric J. Brunner,

Archana SinghManoux,

G. David Batty,

Mika Kivimäki

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.008019

Subject(s) - job strain , medicine , stroke (engine) , hazard ratio , confidence interval , risk factor , relative risk , psychosocial , cohort study , proportional hazards model , physical therapy , psychiatry , mechanical engineering , engineering

Background and Purpose— Psychosocial stress at work has been proposed to be a risk factor for cardiovascular disease. However, its role as a risk factor for stroke is uncertain. Methods— We conducted an individual-participant-data meta-analysis of 196 380 males and females from 14 European cohort studies to investigate the association between job strain, a measure of work-related stress, and incident stroke. Results— In 1.8 million person-years at risk (mean follow-up 9.2 years), 2023 first-time stroke events were recorded. The age- and sex-adjusted hazard ratio for job strain relative to no job strain was 1.24 (95% confidence interval, 1.05;1.47) for ischemic stroke, 1.01 (95% confidence interval, 0.75;1.36) for hemorrhagic stroke, and 1.09 (95% confidence interval, 0.94;1.26) for overall stroke. The association with ischemic stroke was robust to further adjustment for socioeconomic status. Conclusion— Job strain may be associated with an increased risk of ischemic stroke, but further research is needed to determine whether interventions targeting job strain would reduce stroke risk beyond existing preventive strategies.

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