Infarct Volume Prediction by Early Magnetic Resonance Imaging in a Murine Stroke Model Depends on Ischemia Duration and Time of Imaging | Zendy

Christoph Leithner | Zendy; Martina Füchtemeier | Zendy; Devi Jorks | Zendy; Susanne Mueller | Zendy; Ulrich Dirnagl | Zendy; Georg Royl | Zendy

Open Access

Infarct Volume Prediction by Early Magnetic Resonance Imaging in a Murine Stroke Model Depends on Ischemia Duration and Time of Imaging

Author(s) -

Christoph Leithner,

Martina Füchtemeier,

Devi Jorks,

Susanne Mueller,

Ulrich Dirnagl,

Georg Royl

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.007832

Subject(s) - medicine , magnetic resonance imaging , stroke (engine) , ischemia , infarction , effective diffusion coefficient , lesion , cerebral blood flow , nuclear medicine , functional magnetic resonance imaging , cardiology , anesthesia , radiology , surgery , myocardial infarction , mechanical engineering , engineering

Despite standardization of experimental stroke models, final infarct sizes after middle cerebral artery occlusion (MCAO) vary considerably. This introduces uncertainties in the evaluation of drug effects on stroke. Magnetic resonance imaging may detect variability of surgically induced ischemia before treatment and thus improve treatment effect evaluation.

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