Magnetic Resonance Imaging in Experimental Stroke and Comparison With Histology | Zendy

Xenios Milidonis | Zendy; Ian Marshall | Zendy; Malcolm Macleod | Zendy; Emily S. Sena | Zendy

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Magnetic Resonance Imaging in Experimental Stroke and Comparison With Histology

Author(s) -

Xenios Milidonis,

Ian Marshall,

Malcolm Macleod,

Emily S. Sena

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.007560

Subject(s) - medicine , magnetic resonance imaging , stroke (engine) , generalizability theory , histology , radiology , diffusion mri , gold standard (test) , neuroimaging , nuclear medicine , pathology , mechanical engineering , statistics , mathematics , psychiatry , engineering

Because the new era of preclinical stroke research demands improvements in validity and generalizability of findings, moving from single site to multicenter studies could be pivotal. However, the conduct of magnetic resonance imaging (MRI) in stroke remains ill-defined. We sought to assess the variability in the use of MRI for evaluating lesions post stroke and to examine the possibility as an alternative to gold standard histology for measuring the infarct size.

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