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Chronic Ischemia Alters Brain Microstructural Integrity and Cognitive Performance in Adult Moyamoya Disease
Author(s) -
Ken Kazumata,
Khin Khin Tha,
Hisashi Narita,
Ichiro Kusumi,
Hideo Shichinohe,
Masaki Ito,
Naoki Nakayama,
Kiyohiro Houkin
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.114.007407
Subject(s) - fractional anisotropy , white matter , diffusion mri , medicine , posterior cingulate , cardiology , frontal lobe , grey matter , moyamoya disease , neuroscience , magnetic resonance imaging , psychology , radiology , cognition , psychiatry
The mechanisms underlying frontal lobe dysfunction in moyamoya disease (MMD) are unknown. We aimed to determine whether chronic ischemia induces subtle microstructural brain changes in adult MMD and evaluated the association of changes with neuropsychological performance.

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