Norrin Protected Blood–Brain Barrier Via Frizzled-4/β-Catenin Pathway After Subarachnoid Hemorrhage in Rats | Zendy

Yujie Chen | Zendy; Yang Zhang | Zendy; Junjia Tang | Zendy; Fei Liu | Zendy; Qin Hu | Zendy; Chunxia Luo | Zendy; Jiping Tang | Zendy; Hua Feng | Zendy; John H. Zhang | Zendy

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Norrin Protected Blood–Brain Barrier Via Frizzled-4/β-Catenin Pathway After Subarachnoid Hemorrhage in Rats

Author(s) -

Yujie Chen,

Yang Zhang,

Junjia Tang,

Fei Liu,

Qin Hu,

Chunxia Luo,

Jiping Tang,

Hua Feng,

John H. Zhang

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.007265

Subject(s) - evans blue , extravasation , frizzled , occludin , subarachnoid hemorrhage , medicine , dishevelled , blood–brain barrier , anesthesia , pathology , wnt signaling pathway , microbiology and biotechnology , biology , signal transduction , tight junction , central nervous system

Norrin and its receptor Frizzled-4 have important roles in the blood-brain barrier development. This study is to investigate a potential role and mechanism of Norrin/Frizzled-4 on protecting blood-brain barrier integrity after subarachnoid hemorrhage (SAH).

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