Impact of Alcohol Consumption on the Outcome of Ischemic Stroke and Thrombolysis | Zendy

Eloïse Lemarchand | Zendy; Maxime Gauberti | Zendy; Sara Martínez de Lizarrondo | Zendy; Hélène Villain | Zendy; Yohann Repessé | Zendy; Axel Montagne | Zendy; Denis Vivien | Zendy; Carine Ali | Zendy; Marina Rubio | Zendy

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Impact of Alcohol Consumption on the Outcome of Ischemic Stroke and Thrombolysis

Author(s) -

Eloïse Lemarchand,

Maxime Gauberti,

Sara Martínez de Lizarrondo,

Hélène Villain,

Yohann Repessé,

Axel Montagne,

Denis Vivien,

Carine Ali,

Marina Rubio

Publication year - 2015

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.007143

Subject(s) - thrombolysis , medicine , stroke (engine) , magnetic resonance imaging , alcohol , alcohol consumption , tissue plasminogen activator , plasminogen activator , cardiology , radiology , biochemistry , myocardial infarction , mechanical engineering , chemistry , engineering

Tissue-type plasminogen activator (tPA) is the only acute treatment for ischemic stroke. Unfortunately, the benefit of tPA-driven thrombolysis is not systematic, and understanding the reasons for this is mandatory. The balance between beneficial and detrimental effects of tPA might explain the limited overall efficiency of thrombolysis. Here, we investigated whether this balance could be influenced by excessive alcohol intake.

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