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Limited Reliability of Computed Tomographic Perfusion Acute Infarct Volume Measurements Compared With Diffusion-Weighted Imaging in Anterior Circulation Stroke
Author(s) -
Pamela W. Schaefer,
Leticia M Souza,
Shervin Kamalian,
Joshua A Hirsch,
Albert J. Yoo,
Shahmir Kamalian,
Ramón González,
Michael H. Lev
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.114.007117
Subject(s) - medicine , cerebral blood flow , nuclear medicine , perfusion scanning , perfusion , confidence interval , stroke (engine) , diffusion mri , effective diffusion coefficient , blood volume , radiology , magnetic resonance imaging , cardiology , mechanical engineering , engineering
Diffusion-weighted imaging (DWI) can reliably identify critically ischemic tissue shortly after stroke onset. We tested whether thresholded computed tomographic cerebral blood flow (CT-CBF) and CT-cerebral blood volume (CT-CBV) maps are sufficiently accurate to substitute for DWI for estimating the critically ischemic tissue volume.

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