Brain-Derived Neurotrophic Factor Administration Mediated Oligodendrocyte Differentiation and Myelin Formation in Subcortical Ischemic Stroke | Zendy

Jaime RamosCejudo | Zendy; María GutiérrezFernández | Zendy; Laura OteroOrtega | Zendy; Berta RodríguezFrutos | Zendy; Blanca Fuentes | Zendy; María Teresa VallejoCremades | Zendy; Teresa Navarro Hernanz | Zendy; Sebastián Cerdán | Zendy; Exuperio Díez–Tejedor | Zendy

Open Access

Brain-Derived Neurotrophic Factor Administration Mediated Oligodendrocyte Differentiation and Myelin Formation in Subcortical Ischemic Stroke

Author(s) -

Jaime RamosCejudo,

María GutiérrezFernández,

Laura OteroOrtega,

Berta RodríguezFrutos,

Blanca Fuentes,

María Teresa VallejoCremades,

Teresa Navarro Hernanz,

Sebastián Cerdán,

Exuperio Díez–Tejedor

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.006692

Subject(s) - remyelination , oligodendrocyte , medicine , neurotrophic factors , white matter , myelin basic protein , brain derived neurotrophic factor , endocrinology , olig2 , myelin , vascular endothelial growth factor , neuroscience , receptor , central nervous system , magnetic resonance imaging , biology , radiology , vegf receptors

Translational research is beginning to reveal the importance of trophic factors as a therapy for cellular brain repair. The purpose of this study was to analyze whether brain-derived neurotrophic factor (BDNF) administration could mediate oligodendrogenesis and remyelination after white matter injury in subcortical stroke.

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