Von Willebrand Factor Drives the Association Between Elevated Factor VIII and Poor Outcomes in Patients With Ischemic Stroke
Author(s) -
Alyana Samai,
Dominique Monlezun,
Amir Shaban,
Alexander George,
Lauren Dowell,
Rebecca KruseJarres,
Laurie Schluter,
Ramy El Khoury,
Sheryl MartinSchild
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.114.006394
Subject(s) - medicine , odds ratio , von willebrand factor , modified rankin scale , confidence interval , stroke (engine) , risk factor , thrombosis , gastroenterology , ischemic stroke , platelet , ischemia , mechanical engineering , engineering
Despite clear roles of factor VIII (FVIII) and von Willebrand factor (vWF) in thrombosis, few studies have examined the relationship of these factors with acute ischemic stroke (AIS). We sought to determine whether concurrent elevation in FVIII and vWF was associated with adverse events and outcomes.
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