Catabolic Signaling and Muscle Wasting After Acute Ischemic Stroke in Mice | Zendy

Jochen Springer | Zendy; Susanne Schust | Zendy; Katrin Peske | Zendy; Anika Tschirner | Zendy; André Rex | Zendy; Odilo Engel | Zendy; Nadja Scherbakov | Zendy; Andreas Meisel | Zendy; Stephan von Haehling | Zendy; Michael Boschmann | Zendy; Stefan D. Anker | Zendy; Ulrich Dirnagl | Zendy; Wolfram Doehner | Zendy

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Catabolic Signaling and Muscle Wasting After Acute Ischemic Stroke in Mice

Author(s) -

Jochen Springer,

Susanne Schust,

Katrin Peske,

Anika Tschirner,

André Rex,

Odilo Engel,

Nadja Scherbakov,

Andreas Meisel,

Stephan von Haehling,

Michael Boschmann,

Stefan D. Anker,

Ulrich Dirnagl,

Wolfram Doehner

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.006258

Subject(s) - wasting , medicine , catabolism , stroke (engine) , endocrinology , skeletal muscle , myostatin , protein catabolism , sarcopenia , cachexia , anabolism , biology , metabolism , biochemistry , cancer , mechanical engineering , amino acid , engineering

Muscle wasting is a common complication accompanying stroke. Although it is known to impair poststroke recovery, the mechanisms of subacute catabolism after stroke have not been investigated in detail. The aim of this study is to investigate mechanisms of local and systemic catabolism and muscle wasting (sarcopenia) in a model of ischemic stroke systematically.

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