Impact of Time to Treatment on Tissue-Type Plasminogen Activator–Induced Recanalization in Acute Ischemic Stroke | Zendy

Marián Muchada | Zendy; David RodríguezLuna | Zendy; Jorge Pagola | Zendy; Alan Flores | Zendy; Estela Sanjuán | Zendy; Pilar Meler | Zendy; Sandra Boned | Zendy; José ÁlvarezSabín | Zendy; Marc Ribó | Zendy; Carlos A. Molina | Zendy; Marta Rubiera | Zendy

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Impact of Time to Treatment on Tissue-Type Plasminogen Activator–Induced Recanalization in Acute Ischemic Stroke

Author(s) -

Marián Muchada,

David RodríguezLuna,

Jorge Pagola,

Alan Flores,

Estela Sanjuán,

Pilar Meler,

Sandra Boned,

José ÁlvarezSabín,

Marc Ribó,

Carlos A. Molina,

Marta Rubiera

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.006222

Subject(s) - medicine , tissue plasminogen activator , plasminogen activator , stroke (engine) , ischemic stroke , thrombolysis , cardiology , t plasminogen activator , acute stroke , ischemia , surgery , myocardial infarction , mechanical engineering , engineering

Although tissue-type plasminogen activator (tPA) efficacy depends on time, it is unknown whether its effect on recanalization is time dependent. Information about likelihood of successful recanalization as a function of time to treatment may improve patient selection for advanced reperfusion strategies. We aimed to identify the impact of time to treatment on tPA-induced recanalization in patients with acute ischemic stroke.

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