Intracranial Hemorrhage Mortality in Atrial Fibrillation Patients Treated With Dabigatran or Warfarin
Author(s) -
Álvaro Alonso,
Lindsay G.S. Bengtson,
Richard F. MacLehose,
Pamela L. Lutsey,
Lin Y. Chen,
Kamakshi Lakshminarayan
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.114.006016
Subject(s) - medicine , dabigatran , atrial fibrillation , warfarin , stroke (engine) , cardiology , intracranial hemorrhages , intracerebral hemorrhage , subarachnoid hemorrhage , mechanical engineering , engineering
In randomized trials, patients with atrial fibrillation (AF) receiving dabigatran, a direct oral anticoagulant, had lower risk of intracranial bleeding (ICB) than those on warfarin. However, concerns exist about potential worse outcomes in dabigatran users if bleeding occurs, given the lack of approved reversal agents. Thus, we examined in-hospital mortality in AF patients with ICB being treated with dabigatran versus warfarin in a real-world population in the United States.
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