Gene Expression Profiling Reveals Distinct Molecular Signatures Associated With the Rupture of Intracranial Aneurysm | Zendy

Hirofumi Nakaoka | Zendy; Atsushi Tajima | Zendy; Taku Yoneyama | Zendy; Kazuyoshi Hosomichi | Zendy; Hidetoshi Kasuya | Zendy; Tohru Mizutani | Zendy; Ituro Inoue | Zendy

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Gene Expression Profiling Reveals Distinct Molecular Signatures Associated With the Rupture of Intracranial Aneurysm

Author(s) -

Hirofumi Nakaoka,

Atsushi Tajima,

Taku Yoneyama,

Kazuyoshi Hosomichi,

Hidetoshi Kasuya,

Tohru Mizutani,

Ituro Inoue

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.005851

Subject(s) - medicine , gene expression profiling , gene , microarray , gene expression , aneurysm , subarachnoid hemorrhage , locus (genetics) , cdkn2a , pathogenesis , candidate gene , pathology , genetics , biology , surgery

The rupture of intracranial aneurysm (IA) causes subarachnoid hemorrhage associated with high morbidity and mortality. We compared gene expression profiles in aneurysmal domes between unruptured IAs and ruptured IAs (RIAs) to elucidate biological mechanisms predisposing to the rupture of IA.

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