Incidental Magnetic Resonance Diffusion-Weighted Imaging–Positive Lesions Are Rare in Neurologically Asymptomatic Community-Dwelling Adults | Zendy

Saima Batool | Zendy; Martin O’Donnell | Zendy; Mukul Sharma | Zendy; Shofiqul Islam | Zendy; Gilles R. Dagenais | Zendy; Paul Poirier | Zendy; Scott A. Lear | Zendy; Andreas Wielgosz | Zendy; Koon Teo | Zendy; Grant Stotts | Zendy; Cheryl R. McCreary | Zendy; Richard Frayne | Zendy; Jane DeJesus | Zendy; Sumathy Rangarajan | Zendy; Salim Yusuf | Zendy; Eric E. Smith | Zendy

Open Access

Incidental Magnetic Resonance Diffusion-Weighted Imaging–Positive Lesions Are Rare in Neurologically Asymptomatic Community-Dwelling Adults

Author(s) -

Saima Batool,

Martin O’Donnell,

Mukul Sharma,

Shofiqul Islam,

Gilles R. Dagenais,

Paul Poirier,

Scott A. Lear,

Andreas Wielgosz,

Koon Teo,

Grant Stotts,

Cheryl R. McCreary,

Richard Frayne,

Jane DeJesus,

Sumathy Rangarajan,

Salim Yusuf,

Eric E. Smith

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.005782

Subject(s) - medicine , cerebral amyloid angiopathy , asymptomatic , magnetic resonance imaging , intracerebral hemorrhage , stroke (engine) , population , radiology , confidence interval , diffusion mri , epidemiology , leukoaraiosis , hyperintensity , pathology , dementia , surgery , glasgow coma scale , disease , mechanical engineering , environmental health , engineering

Background and Purpose— Incidental magnetic resonance diffusion-weighted imaging (DWI)–positive lesions, considered to represent small acute infarcts, have been detected in patients with cerebral small vessel diseases or cognitive impairment, but the prevalence in the community population is unknown. Methods— DWI sequences collected in 793 participants in the Prospective Urban Rural Epidemiological (PURE) study were reviewed for DWI lesions consistent with small acute infarcts. Results— No DWI-positive lesions were detected (0%, 95% confidence interval, 0–0.5). Conclusions— DWI-positive lesions are rare in an asymptomatic community population. The prevalence of DWI-positive lesions in the community seems to be lower than in patients with cerebral amyloid angiopathy, intracerebral hemorrhage, or cognitive impairment.

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