Open AccessTime and Diffusion Lesion Size in Major Anterior Circulation Ischemic Strokes
Author(s) -
Reza Hakimelahi,
Behroze Vachha,
William A. Copen,
Giacomo Davide Edoardo Papini,
Julian He,
Mahmoud M. Higazi,
Michael H. Lev,
Pamela W. Schaefer,
Albert J. Yoo,
Lee H. Schwamm,
Ramón González
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.114.005644
Subject(s) - medicine , collateral circulation , middle cerebral artery , internal carotid artery , stroke (engine) , anterior cerebral artery , cardiology , perfusion , infarction , perfusion scanning , lesion , radiology , cerebral infarction , ischemia , surgery , myocardial infarction , mechanical engineering , engineering
Major anterior circulation ischemic strokes caused by occlusion of the distal internal carotid artery or proximal middle cerebral artery or both account for about one third of ischemic strokes with mostly poor outcomes. These strokes are treatable by intravenous tissue-type plasminogen activator and endovascular methods. However, dynamics of infarct growth in these strokes are poorly documented. The purpose was to help understand infarct growth dynamics by measuring acute infarct size with diffusion-weighted imaging (DWI) at known times after stroke onset in patients with documented internal carotid artery/middle cerebral artery occlusions.
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