Altered Astrocyte–Neuronal Interactions After Hypoxia-Ischemia in the Neonatal Brain in Female and Male Rats | Zendy

Tora Sund Morken | Zendy; Eva Brekke | Zendy; Asta K. Håberg | Zendy; Marius Widerøe | Zendy; AnnMari Brubakk | Zendy; Ursula Sonnewald | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Altered Astrocyte–Neuronal Interactions After Hypoxia-Ischemia in the Neonatal Brain in Female and Male Rats

Author(s) -

Tora Sund Morken,

Eva Brekke,

Asta K. Håberg,

Marius Widerøe,

AnnMari Brubakk,

Ursula Sonnewald

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.114.005341

Subject(s) - medicine , astrocyte , hypoxia (environmental) , ischemia , brain ischemia , neuroscience , endocrinology , central nervous system , physiology , anesthesia , chemistry , organic chemistry , oxygen , biology

Increased susceptibility to excitotoxicity of the neonatal brain after hypoxia-ischemia (HI) may be caused by limited capacity of astrocytes for glutamate uptake, and mitochondrial failure probably plays a key role in the delayed injury cascade. Male infants have poorer outcome than females after HI, possibly linked to differential intermediary metabolism.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research