Neuroprotection of Ischemic Postconditioning by Downregulating the Postsynaptic Signaling Mediated by Kainate Receptors | Zendy

Jing Liu | Zendy; Qin Xu | Zendy; Hui Wang | Zendy; Ran Wang | Zendy; Xiaoyu Hou | Zendy

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Neuroprotection of Ischemic Postconditioning by Downregulating the Postsynaptic Signaling Mediated by Kainate Receptors

Author(s) -

Jing Liu,

Qin Xu,

Hui Wang,

Ran Wang,

Xiaoyu Hou

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.680181

Subject(s) - medicine , neuroprotection , postsynaptic potential , kainate receptor , neuroscience , receptor , pharmacology , glutamate receptor , ampa receptor , biology

Ischemic postconditioning, a brief episode of ischemia after a prolonged ischemic insult, has been found to reduce the delayed neuronal loss after stroke. However, the mechanisms underlying such endogenous neuroprotective strategy remain obscure. In this study, we try to explore the excitatory postsynaptic signal events associated with neuroprotective effect of ischemic postconditioning.

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