Hyperglycemia Exacerbates Intracerebral Hemorrhage via the Downregulation of Aquaporin-4 | Zendy

ChengDi Chiu | Zendy; Chiao-Chi V. Chen | Zendy; ChiungChyi Shen | Zendy; Li-Te Chin | Zendy; Hsin-I Ma | Zendy; Hao-Yu Chuang | Zendy; DerYang Cho | Zendy; ChiHong Chu | Zendy; Chen Chang | Zendy

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Hyperglycemia Exacerbates Intracerebral Hemorrhage via the Downregulation of Aquaporin-4

Author(s) -

ChengDi Chiu,

Chiao-Chi V. Chen,

ChiungChyi Shen,

Li-Te Chin,

Hsin-I Ma,

Hao-Yu Chuang,

DerYang Cho,

ChiHong Chu,

Chen Chang

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.675983

Subject(s) - medicine , intracerebral hemorrhage , downregulation and upregulation , stroke (engine) , complication , aquaporin , anesthesia , subarachnoid hemorrhage , physiology , mechanical engineering , biochemistry , chemistry , engineering , gene

Intracerebral hemorrhage (ICH) is associated with high mortality and neurological deficits, and concurrent hyperglycemia usually worsens clinical outcomes. Aquaporin-4 (AQP-4) is important in cerebral water movement. Our aim was to investigate the role of AQP-4 in hyperglycemic ICH.

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