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Fluid-Attenuated Inversion Recovery Hyperintensity Correlates With Matrix Metalloproteinase-9 Level and Hemorrhagic Transformation in Acute Ischemic Stroke
Author(s) -
Ruchira M. Jha,
Thomas W.K. Battey,
Ly Pham,
Svetlana Lorenzano,
Karen L. Furie,
Kevin N. Sheth,
W. Taylor Kimberly
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.004627
Subject(s) - medicine , stroke (engine) , ischemic stroke , acute stroke , matrix metalloproteinase 9 , cardiology , fluid attenuated inversion recovery , matrix metalloproteinase , magnetic resonance imaging , ischemia , tissue plasminogen activator , radiology , mechanical engineering , engineering
Matrix metalloproteinase-9 (MMP-9) is elevated in patients with acute stroke who later develop hemorrhagic transformation (HT). It is controversial whether early fluid-attenuated inversion recovery (FLAIR) hyperintensity on brain MRI predicts hemorrhagic transformation (HT). We assessed whether FLAIR hyperintensity was associated with MMP-9 and HT.

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