Response to Letter Regarding Article, “Serum Alkaline Phosphatase and Phosphate in Cerebral Atherosclerosis and Functional Outcomes After Cerebral Infarction” | Zendy

Jinkwon Kim | Zendy; Ji Hoe Heo | Zendy

Open Access

Response to Letter Regarding Article, “Serum Alkaline Phosphatase and Phosphate in Cerebral Atherosclerosis and Functional Outcomes After Cerebral Infarction”

Author(s) -

Jinkwon Kim,

Ji Hoe Heo

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.004281

Subject(s) - medicine , cerebral infarction , alkaline phosphatase , stroke (engine) , neurology , vitamin d and neurology , cerebral atherosclerosis , endocrinology , cardiology , cerebral arteries , biochemistry , ischemia , psychiatry , enzyme , mechanical engineering , chemistry , engineering

We appreciate the interest of Dr Tsuda in our recently published article.1 In our study, we showed that higher levels of alkaline phosphatase (ALP) were associated with a poor functional outcome after acute stroke, but phosphate was not. Dr Tsuda wanted to know whether the levels of ALP/phosphate were correlated with changes in bone mineral density (BMD) and serum vitamin D levels. Dr Tsuda’s questions were based on evidence that (1) there was an association between BMD and stroke; (2) lower serum 25-hydroxyvitamin D levels were associated with carotid atherosclerosis and fatal …

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