Retinal Microvascular Abnormalities Predict Progression of Brain Microvascular Disease | Zendy

Thomas C. Hanff | Zendy; A. Richey Sharrett | Zendy; Thomas H. Mosley | Zendy; Dean Shibata | Zendy; David S. Knopman | Zendy; Ronald Klein | Zendy; Rebecca F. Gottesman | Zendy

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Retinal Microvascular Abnormalities Predict Progression of Brain Microvascular Disease

Author(s) -

Thomas C. Hanff,

A. Richey Sharrett,

Thomas H. Mosley,

Dean Shibata,

David S. Knopman,

Ronald Klein,

Rebecca F. Gottesman

Publication year - 2014

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.004166

Subject(s) - medicine , retinal , disease , stroke (engine) , retina , microcirculation , ophthalmology , pathology , cardiology , neuroscience , mechanical engineering , biology , engineering

Brain microvascular disease leads to leukoaraiosis and lacunar infarcts and contributes to risk of stroke and cognitive decline. Given a shared pathophysiology, retinal microvascular signs are expected to predict brain microvascular disease progression. We investigated if either leukoaraiosis volume progression measured continuously or combined with incident lacunar infarcts would better demonstrate expected associations with retinal disease than has previously been shown.

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