Iodinated Contrast Does Not Alter Clotting Dynamics in Acute Ischemic Stroke as Measured by Thromboelastography
Author(s) -
Mark McDonald,
Joancy Archeval-Lao,
Chunyan Cai,
Hui Peng,
Navdeep Sangha,
Stephanie Parker,
Jeremy Wetzel,
Stephen A Riney,
Matt F. Cherches,
Greer J. Guthrie,
Tiffany C. Roper,
Jorge Kawano-Castillo,
Renga Pandurengan,
Mohammad H. Rahbar,
James C. Grotta
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.003268
Subject(s) - medicine , thromboelastography , thrombolysis , fibrinolysis , tissue plasminogen activator , iodixanol , fibrinolytic agent , stroke (engine) , angiography , iodinated contrast , anesthesia , cardiology , radiology , myocardial infarction , contrast medium , coagulation , computed tomography , mechanical engineering , engineering
Iodinated contrast agents used for computed tomography angiography (CTA) may alter fibrin fiber characteristics and decrease fibrinolysis by tissue plasminogen activator (tPA). Thromboelastography (TEG) measures the dynamics of coagulation and correlates with thrombolysis in acute ischemic stroke patients. We hypothesized that receiving CTA before tPA will not impair thrombolysis as measured by TEG.
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